Three Elderly Cases with Brugada-type Electrocardiographic Pattern Unmasked by Pilsicainide at the Toxic Level

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Brugada-type Electrocardiographic Pattern Induced by Fever

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[Electrocardiographic findings typical of Brugada syndrome unmasked by cocaine consumption].

Brugada syndrome is characterized by the presence of right bundle branch block on electrocardiography and by ST-segment elevation in the right precordial leads (V1-V3), by the absence of structural cardiac abnormalities, and by episodes of syncope or sudden death. On occasion, diagnosis is made difficult by temporary normalization of the ECG. The condition can be unmasked by potent sodium chann...

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Brugada-like electrocardiographic pattern unmasked by fever in a critical care patient.

Sir, Brugada syndrome is a channelopathy associated with right bundle branch block and ST segment elevation in the right precordial leads, V1–V3, in the absence of structural heart abnormalities (1). Mutations in a cardiac sodium channel gene (SCN5A) have been reported as the substrate for the syndrome in some patients (2). Past studies suggested that fever could aggravate the dysfunction of th...

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ژورنال

عنوان ژورنال: Internal Medicine

سال: 2005

ISSN: 0918-2918,1349-7235

DOI: 10.2169/internalmedicine.44.55